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The Most Affordable HiFi Genome Yet

New SPRQ-Nx chemistry reduces costs and adds multiomic capabilities. Be among the first to experience richer data, lower price per genome, and flexibility.

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A First-of-Its-Kind Treat

We’ve never done this before: a genomics conference giveaway for 2026. Enter before the holidays for your shot at getting travel, accommodations, and registration covered at any conference you choose. No tricks, just treats. There’s HiFi for that.

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WEBINAR: HiFi sequencing for antibody development

In this webinar, you’ll learn how HiFi sequencing can be used to enable antibody development and how it improves downstream outcomes. See how HiFi enables full-length reads of constructs like scFv and Fab with 99.9% accuracy and the throughput needed for confident clone selection.

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Sequencing methods for solutions that matter

Our technology provides the most comprehensive view of genomes, transcriptomes, and epigenomes.

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Whole genome sequencing

Achieve the highest consensus accuracy and uniform coverage for reference quality genomes in humans, plants, animals, and microbes.

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Targeted sequencing

Accurately detect and uncover all variant types even in hard-to-reach regions of the genome.

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Epigenetics

Explore how epigenetic changes affect gene expression, host-pathogen interactions, environmental response, and more.

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RNA sequencing

Discover new genes, transcripts, and alternative splicing events with a complete view of transcript isoform diversity.

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Accelerate your research

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  • Microbial genomics
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Application note

Kinnex full-length RNA Kit for isoform sequencing

The Kinnex full-length RNA kit for bulk RNA sequencing produces 15 million reads and 40 million reads per SMRT Cell on Sequel II and Revio systems. This represents a 15-fold throughput increase on Revio with Kinnex.

See how

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A roadmap to expand PureTarget repeat expansion and carrier panels, enabling high-throughput clinical research solutions

Introducing two new panels – an updated repeat expansion panel and a new carrier screening panel – plus a 96-plex automation kit and a full software pipeline for carrier screening. Together, these tools streamline legacy assays into one efficient, high-throughput workflow to provide more value for key applications in clinical and diagnostic research and carrier screenin

Learn more

Sequencing 101: Long-read sequencing

Long-read sequencing technologies are quickly becoming the new gold standard in genomics research, and HiFi sequencing is at the forefront. This article provides an introductory look at what long-read sequencing is, and explores topics the advantages, applications of using long-read sequencing in your research.

Learn more

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What can you do with a Revio system?

Access more information at reduced cost and higher throughput with Revio long-read sequencing.

See what you can get

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10,000+ articles, reports, papers, and videos

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Recent press

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  • PacBio Announces Third Quarter 2025 Financial Results
    November 05, 2025 | GLOBE NEWSWIRE

  • PacBio Announces Third Quarter 2025 Financial Results
    November 05, 2025 | GLOBE NEWSWIRE

  • HiFi Solves Consortium Publishes First Major Study Demonstrating the Clinical Research Power of PacBio HiFi Genomes
    November 05, 2025 | GLOBE NEWSWIRE

View all

Recent articles

  • Powered by PacBio:
    Selected publications from October 2025
    November 07, 2025

  • Publication spotlight:
    Capturing the full picture of genome editing with custom PureTarget panels
    October 30, 2025

  • Customer success story:
    How two University of Michigan cores use HiFi sequencing to cut costs, save time, and improve accuracy in transgenic models
    October 22, 2025

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